| Acronym | Meaning |
 | INSURV | Board Of Inspection And Survey |
| INTENS | Intensity |
| INTER | Intermediate |
| INU | Inertial Navigation Unit |
| IOC | Initial Operational Capability |
| IOP | Input/output Processor |
| IOPB | Input/output Parameter Buffer |
| IOS | Instructor Operator Station |
| IPL | Initial Program Load |
| IPR | Ils Program Review |
| IPR | In-process Review |
| IPS | Ice Protection System |
| IPS | Inches Per Secon |
| IPS | Inlet Particle Separator |
| IPSC | Ice Protection System Controler |
| IPSC | Information Processing Standards For Computers |
| IPU | Inert Prefill Unit |
| IQC | Indefinite Quantity Contract |
| IR | Infrared |
| IR&D | Independent Research & Development |
| IRAC | Interim Rapid Action Change |
| IRAC | International Requirements & Criteria |
| IRDS | Information Resource Dictionary System |
| IRDS | Infrared Detecting System |
| IRGP | Infrared Guided Projectile Weapon System 5 |
| IRIG | Inertial Rate Integrating Gyrominter |
| IRJ | Infrared Jammer |
| IRMO | Information Resources Management Officer |
| IRP | Intermediate Rated Power (30 Minutes) |
| IRS | Infared Suppressor |
| IRS | Interface Requirements Specification |
| IRST | Infrared Search And Track System |
| ISAM | Indexed Sequential Access Method |
| ISARS | Improved Ssbn Recorder Outline System (an/bqh-8) |
| ISC | Icing System Controller |
| ISC | Intercommunication Set Control |
| ISD | Instructional Systems Development |
| ISE | In-service Engineer |
| ISEE | Integrated Software Engineering Environment |
| ISEO | In-service Engineering Office |
| ISG | Instructional Systems Group |
| ISI | Information Spectrum Inc |
| ISI | Interim Support Item |
| ISIL | Interim Support Items List |
| ISIP | Immediate Superior In Command |
| ISLN | Isolation |
| ISM | Input Signal Management |
| ISOL | Isolation |
| ISP | Integrated Support Plan |
| ISP | Interim Support Period |
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