| Acronym | Meaning |
 | UGX | Ugandan Shilling (ISO 4217 Currency Code) |
| UHF | Ultra High Frequency |
| UHMW | Ultra-High Molecular Weight |
| UHRB | Ultra-High Resolution Building (simulation) |
| UIC | University Of Illinois At Chicago |
| UID | User ID |
| UIG | Uyghur Language (ISO 639-2 Code) |
| UIUC | University Of Illinois At Urbana-Champaign |
| UJTL | Universal Joint Task List |
| UK | United Kingdom (alsoFIPS 10-4 Country Code) - University Of Kentucky |
| UK | Ukrainian Language (ISO 639-1 Code) |
| UKR | Ukraine (ISO 3166 Trigram) |
| UKR | Ukrainian Language (ISO 639-2 Code) |
| UL | Underwriters Laboratories |
| ULEB | Union Des Ligues Europ?ens De Basket-ball |
| ULF | Ultra Low Frequency |
| UM | U.S. Minor Outlying Islands (postal Symbol; ISO 3166 Digram) |
| UMBC | University Of Maryland Baltimore County |
| UMC | United Microelectronics Corporation |
| UMCP | Unit Maintenance Collection Point |
| UMES | University Of Maryland Eastern Shore |
| UMI | U.S. Minor Outlying Islands (ISO 3166 Trigram) |
| UMIST | University Of Manchester Institute Of Science And Technology |
| UMK | Uniwersytet Miko?aja Kopernika (Polish Nicolaus Copernicus University) |
| UML | Unified Marxist-Leninist Communist Party Of Nepal - Unified Modeling Language - University Of Massachusetts Lowell - User-Mode Linux |
| UMTS | Universal Mobile Telecommunications System |
| UN | United Nations |
| UNABOM | University And Airline Bomber (FBI Case Name) |
| UNAIDS | Joint United Nations Programme On HIV/AIDS |
| UNAMSIL | United Nations Mission In Sierra Leone |
| UNCF | United Negro College Fund |
| UNCLOS | United Nations Convention On The Law Of The Sea |
| UNCSGN | United Nations Conference On The Standardization Of Geographical Names |
| UNCTAD | United Nations Conference On Trade And Development |
| UNDCP | United Nations Drug Control Programme |
| UNDE | Union Of National Defence Employees (Canada) |
| UNDP | United Nations Development Programme |
| UNEP | United Nations Environment Programme |
| UNESCO | United Nations Educational |
| UNFCCC | United Nations Framework Convention On Climate Change |
| UNFICYP | United Nations Peacekeeping Force In Cyprus |
| UNGEGN | United Nations Group Of Experts On Geographic Names |
| UNHCR | United Nations High Commission(er) For Refugees |
| UNICEF | United Nations Children's Fund (originally The United Nations International Children's Emergency Fund) |
| UNICRI | United Nations Interregional Crime And Justice Research Institute |
| UNIDO | United Nations Industrial Development Organization |
| UNIFEM | United Nations Development Fund For Women |
| UNIS | University Of Surrey |
| UNLV | University Of Nevada |
| UNMIK | United Nations Interim Administration Mission In Kosovo |
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