| Acronym | Meaning |
 | TYCLO | Turn Your CAPS LOCK Off |
| TYVM | Thank You Very Much |
| U | You |
| U UP | Are You Up? |
| U-L | You Will |
| U2 | You Too |
| U8 | You Ate? |
| UBS | Unique Buying State |
| UCWAP | Up A Creek Without A Paddle |
| UDH82BME | You'd Hate To Be Me |
| UG2BK | You've Got To Be Kidding |
| UGC | User-Generated Content |
| UL | You Will |
| UNPC | UnPolitically Correct |
| UNTCO | You Need To Chill Out |
| UOK | Are You OK? |
| UPOD | Under Promise, Over Deliver |
| UR | You Are |
| UR2K | You Are Too Kind |
| URAPITA | You Are A Pain In The Ass |
| URSAI | You Are Such An Idiot |
| URT1 | You Are The One |
| URW | You Are Welcome |
| URWS | You Are Wise |
| URYY4M | You Are Too Wise For Me |
| US | Utter Sh*t |
| US | You Suck |
| USP | Unique Selling Proposition |
| UTM | You Tell Me |
| UV | Unpleasant Visual |
| UWIWU | You Wish I Was You |
| VBG | Very Big Grin |
| VBS | Very Big Smile |
| VC | Venture Capital |
| VCDA | Vaya Con Dios, Amigo (Go With God, Friend) |
| VEG | Very Evil Grin |
| VFM | Value For Money |
| VGN | Vegan / Vegetarian |
| VM | Voice Mail |
| VRBS | Virtual Reality Bull Sh*t |
| VRI | Very |
| VSF | Very Sad Face |
| VWD | Very Well Done |
| VWP | Very Well Played |
| W/ | With |
| W/O | Without |
| W00T | We Own The Other Team. Often Used As An Expression Of Joy. |
| W4U | Waiting For You |
| W8 | Wait |
| WAD | Without A Doubt |
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