| Acronym | Meaning |
| OSIF | Oh Sh*t I Forgot |
| OSINTOT | Oh Sh*t I Never Thought Of That |
| OST | On Second Thought |
| OT | Off Topic |
| OTASOIC | Owing To A Slight Oversight In Construction |
| OTC | Over The Counter |
| OTF | Off The Floor |
| OTF | On The Phone (Fone) |
| OTH | Off The Hook |
| OTL | Out To Lunch |
| OTOH | On The Other Hand |
| OTP | On The Phone |
| OTT | Over The Top |
| OTTOMH | Off The Top Of My Head |
| OTW | Off The Wall |
| OUSU | Oh, You Shut Up |
| OWTTE | Or Words To That Effect |
| OZ | Australia |
| P | Partner |
| P&C | Private & Confidential |
| P-ZA | Pizza |
| P2C2E | Process Too Complicated Too Explain |
| P911 | Parent Alert |
| PA | Parent Alert |
| PAL | Parents Are Listening |
| PANS | Pretty Awesome New Stuff |
| PAW | Parents Are Watching |
| PB | Potty Break |
| PBB | Parent Behind Back |
| PBEM | Play By EMail |
| PBJ | Peanut Butter And Jelly |
| PBJ | Pretty Boy Jock |
| PCM | Please Call Me |
| PD | Public Domain |
| PDOMA | Pulled Directly Out Of My Ass |
| PDQ | Pretty Darn Quick |
| PDS | Please Don't Shout |
| PEBCAC | Problem Exists Between Chair And Computer |
| PEBCAK | Problem Exists Between Chair And Keyboard |
| PFA | Please Find Attached |
| PFA | Pulled From Ass |
| PFC | Pretty F*cking Cold |
| PHAT | Pretty Hot And Tempting |
| PHB | Pointy Haired Boss |
| PHS | Pointy Haired Stupidvisor |
| PIAPS | Pig In A Pant Suit |
| PIBKAC | Problem Is Between Keyboard And Chair |
| PICNIC | Problem In Chair, Not In Computer |
| PIF | Paid In Full |
| PIMP | Peeing In My Pants |