| Acronym | Meaning |
 | MMC | Mid Motor Controller |
| MMC | Mission Management Center |
| MMCA | Mid Motor Controller Assembly |
| MMCA | Midbody Motor Control Assembly |
| MMCL | Master Measurement And Control List |
| MMDB | Mass Memory Data Base |
| MMDB | Master Measurement Data Base |
| MMDF | Mission Model Data File |
| MMES | MSFC Mated Element Systems |
| MMH | Maintenance Man-Hour |
| MMH | Monomethyl Hydrazine |
| MMH | Monomethylhydrazine |
| MML | Master Measurement(s) List |
| MMLS | Model-Modes-Loads-Stresses |
| MMOS | Multimode Optical Sensor |
| MMPSE | Multiuse Mission Payload Support Equipment |
| MMS | Mission Modular Spacecraft |
| MMS | Modular Multiband Scanner |
| MMS | Multimission Modular Spacecraft |
| MMS | Multimission Modular Spacecraft |
| MMSE | Multiuse Mission Support Equipment |
| MMSE | Multiuse Mission Support Equipment |
| MMT | Mass Memory Test |
| MMU | Manned Maneuvering Unit |
| MMU | Manned Maneuvering Unit |
| MMU | Mass Memory Unit |
| MMU | Mass Memory Unit |
| MN | Main |
| MNA | B |
| MNVR | Maneuver |
| MO | Major Objective |
| MO | Manned Orbiter |
| MO | Manual Orientation |
| MO | Manufacturing Order |
| MO | Master Oscillator |
| MO | Middeck Overhead |
| MO | Mission Operations |
| MO | Molybdenum |
| MO | Move |
| MOA | Make On Arrival |
| MOA | Memorandum Of Agreement |
| MOA | Minute-of-Angle |
| MOC | Marine Operation Center |
| MOC | Mission Operations Computer |
| MOCF | Mission Operations Computational Facilities |
| MOCR | Mission Operations Control Room |
| MOCS | Multichannel Ocean Color Sensor |
| MOCV | Manual 02 Control Valve |
| MOD | Modulation |
| MOD | Module |
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