| Acronym | Meaning |
| CST | Contract Supplemental Tooling |
| CST | Crew Station Trainer |
| CST | Crew Systems Trainer (One-G Trainer) |
| CSTA | Crew Software Training Aid |
| CSTR | Canister |
| CSTS | Cryogenic Storage And Transfer System |
| CT | Crawler Transporter |
| CT | Current Transformer |
| CTA | Computer Technology Associates (GSFC) |
| CTA | Controlled ThrustAssembly |
| CTC | Camera |
| CTC | Chief Test Conductor |
| CTE | CentralTimingEquipment |
| CTI | Critical Transportation Item |
| CTIS | Crawler Transporter Intercom System |
| CTL | Canoga Test Laboratory |
| CTL | Central Or Control |
| CTM | Contract TechnicalManager |
| CTM | Crystalline Transitional Material |
| CTN | Certification TestNetwork |
| CTP | Communications Timing Procedure |
| CTP | CYclic Time Processor |
| CTPD | Crew Training And Procedures Division (JSC) |
| CTR | Contract Technical Representative |
| CTRS | Component Test Requirements Specifications |
| CTS | Canadian Technology Satellite |
| CTS | Ci'mPuter Test Set |
| CTS | Communications And Tracking System |
| CTS | COMPuterized Training System |
| CTSD | ComPuter Test Sequences Document |
| CTSD | Coordinate Transformation SYstem |
| CTTB | Checkout Techniques Test Bed |
| CTU | Central Timing Unit |
| CTWT | Counterweight |
| CU | Control Unit |
| CU | Cubic |
| CUB | Commonality Usage Board |
| CUC | ComPuter Usage Control |
| CUDS | Cumulative Data Statistics |
| CUE | Common Usage Equipment |
| CUF | Cross Utilization File |
| CUIL | COmmon Usage Item List |
| CUM | Cumulative |
| CUP | Commonality Usage ProPosal |
| CV | Check Valve |
| CV | Coefficient Of Variation |
| CV | Deployable Payloads Operation (KSC Co Dir.) |
| CV | Expendable Vehicles Operations (KSC Directorate) |
| CVAD | Converter |
| CVAS | Configuration Verification Accounting System |