| Acronym | Meaning |
 | CP-PCO | Cargo Projects-Program Control Office |
| CP-SPO | Spacelab Projects Office (KSC) |
| CPA | Contingency Planning Aid |
| CPA | Critical Path Analysis |
| CPAF | Cost Plus Award Fee |
| CPC | Central Planning Center |
| CPC | Characteristics Properties Code |
| CPC | ComputerProgramComponent |
| CPC | I Computer Program Change Instruction |
| CPCB | Crew Procedures ControlBoard |
| CPCEI | Computer Program Contract End Item |
| CPCI | Computer Prograni Configuration Item |
| CPCL | Computer Program Change Library |
| CPCL | Computer Program Control Library |
| CPCR | Computer Program Change Request |
| CPCR | Crew Procedures Change Request (Form 482) |
| CPD | Converter |
| CPD | Crew ProceduresDivision |
| CPD | Crew Passive Dosimeter |
| CPD | R Contractor's Preliminary Design Review |
| CPDDS | COmPuter Program Detail Design Specification |
| CPDS | Computer Program Design (or Development) Specificat |
| CPDS | Crew Procedures Documentation System |
| CPE | Chief Program Engineer |
| CPE | I Computer Program End Item |
| CPES | Crew Procedures Evaluation (Evaluator) Simulator |
| CPF | Cargo Processing Facility |
| CPF | Central Processing Facility |
| CPF | Cost Per Flight |
| CPFF | COst Plus Fixed Fee |
| CPG | Change Planning Group |
| CPI | Cross Pointer Indicator |
| CPI | Crosspointer Indicator |
| CPIF | COst Plus Incentive Fee |
| CPL | Couple |
| CPLT | Complete |
| CPM | ComputerProgramModule |
| CPM | Critical Path Method |
| CPM | Cycles Per Minute |
| CPMP | Crew Procedures Management Plan |
| CPR | Critical Problem Report |
| CPS | Cycles Per Second |
| CPSE | Common Payload SuPport EquiPment |
| CPSS | Cold Plate Support Structure |
| CPSS | Critical Phase System Software |
| CPT | Cargo Processing Technician |
| CPT | Computer Program Tapes |
| CPU | Central Processing Unit |
| CPU | Central Processor Unit |
| CPU | Computer Printer Unit |
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