| Acronym | Meaning |
 | SEACF | Support Equipment Assembly And Checkout Facility |
 | SEADS | Shuttle Entry Air Data Sensor |
 | SEADS | Shuttle Entry Air Data System |
 | SEADS | Shuttle EntrY Air Data System (Subsystem) |
 | SEAID | SuPport Equipment Abbreviated Items Description |
 | SEAPG | Support Equipment Acquisition Planning Group |
 | SEARCHS | Shuttle Engineer' |
 | SEARCHS | Simulation |
 | SEB | Scientific Equipment Bay |
 | SEB | Source Evaluation Board |
 | SEB | Support Equipment Building |
 | SEB | SYstems Engineering Branch |
 | SEC | Second |
 | SEC | Secondary |
 | SEC | Secondary |
 | SEC | Sequential Events Controller |
 | SEC | Source Evaluation Committee |
 | SECO | Sustainer Engine Cutoff |
 | SECS | Shuttle Events Control |
 | SECS | Standard Cubic Centimeters Per Second |
 | SEE | Special Purpose End Effector |
 | SEE | Standard End Effector |
 | SEE | Subsystem |
 | SEG | Segment |
 | SEI | SuPPort EquiPment Installation |
 | SEI | SYstem Engineering Groundrule |
 | SEICO | SuPPort EquiPment Installation And Checkout |
 | SEICO | System Engineering Instrumentation |
 | SEL | Select |
 | SEM | Scanning Electron Microscope |
 | SEM | Seller's Engineering Memo |
 | SEM | Space Environment Monitoring |
 | SEM | System Engineering Management |
 | SEMS | Space Environment Monitor System |
 | SEN | Sensor |
 | SEND | Shared Equipment Need Date |
 | SENS | Sensitivity |
 | SEO | Special Engineering Order |
 | SEOS | Synchronous Earth Observation Satellite |
 | SEP | Separation |
 | SEP | Source Evaluation Panel |
 | SEP | SUPPort Equipment Package |
 | SEPAP | Shuttle Electrical Power Analysis Program |
 | SEPAR | Shuttle Electrical Power Analysis Report |
 | SEPS | Solar Electric Propulsion System |
 | SEQ | Sequence |
 | SER | Serial |
 | SERB | Shuttle Engineering Review Board |
 | SERB | Systems Engineering Review Board |
 | SERS | Shuttle Equipment Record System |