| Acronym | Meaning |
 | PIC | Payload Integration Center |
| PIC | Payload Integration Committee |
| PIC | Preinstallation Checkout |
| PIC | Programmable Interval Clock |
| PIC | Pyro Ignition Control |
| PIC | Pyro Initiator Capacitors |
| PIC | Pyro Initiator Controller |
| PIC | Pyro Initiator Controller |
| PIC | Pyrotechnic Initiator Controller |
| PICP | Program Interface Control Plan |
| PICRS | Program Information Control And Retrieval System |
| PICRS | Program Information Coordination And Review |
| PICRS | Service |
| PICS | Photo Index And Cataloging System |
| PICS | Predefined Input Control Sequence |
| PID | Payload Insertion Device |
| PID | Program Information Document |
| PID | Program Introduction Document |
| PIDA | Payload Installation And Deployment Aid |
| PIDS | Portable Image Display System |
| PIE | P/L Integration Equipment |
| PIECP | Preliminary Impact Engineering Change Proposal |
| PIF | Payload Integration Facility |
| PIGA | Pendulous Integrating Gyro Accelerometer |
| PIIN | Procurement Instrument Identification Number |
| PIL | Procurement Instrument Identification |
| PIM | Pulse Interval Modulation |
| PIND | Particle Impact Noise Detection |
| PIO | Payload Integration Plan |
| PIO | Pilot-Induced Oscillation |
| PIO | Public Information Office |
| PIP | Payload Integration Plan |
| PIP | Payload Interface Plan |
| PIP | Plant Instrumentation Program |
| PIP | Production Instrumentation Package |
| PIP | Project Implementation Plan |
| PIPA | Pulse Integrating Pendulum Accelerometers |
| PIPA | Pulse Integrating Pendulum Assembly |
| PIRN | Preliminary Interface Revision Notice |
| PIT | Preinstallation Test |
| PITG | Payload Integration Task Group |
| PITS | Payload Integration Test Set |
| PIU | Power Interface Unit |
| PIU | Pyrotechnic Initiator Unit |
| PIV | Peak Inverse Voltage |
| PK | Peak (Valve) |
| PK/PK | Peak To Peak |
| PKD | Programmable Keyboard And Display |
| PKG | Package |
| PKM | Perigee KickMotor |
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