| Acronym | Meaning |
 | PED | Pedal |
| PED | Pedestal |
| PEFO | Payload Effects Follow-on Study |
| PEG | Powered Explicit Guidance |
| PEIR | Project Equipment Inspection Record |
| PEM | Plant Engineering And Maintenance |
| PEN | Penicillin |
| PEP | Power Extension Package |
| PER | Perigee |
| PER | Period |
| PER | Preliminary Engineering Report |
| PERF | Perform |
| PERIGEE | AlPerigee Altitude |
| PERM | Permanent |
| PERT | Program Evaluation Review Technique |
| PET | Phase Elapsed Time |
| PETA | Performance Evaluation And Trend Analysis |
| PETB | Preflight Test Bus |
| PETN | Petaerythrite Tetranitrate |
| PETS | P/L Experiment Test System (KSC) |
| PETS | Payload Environmental Transportation System |
| PETS | POCC Experiments Timeline System (GDSD And Spacelab |
| PF | Parachute Facility |
| PF | PayloadForward |
| PF | PayloadFunction |
| PF | Payload Operational Instrumentation MDM-FWD |
| PF | Power Factor |
| PF | PoweredFlight |
| PF | Preflight |
| PF | PrimeFunction |
| PF | Probability Of Failure |
| PF | Pulse Frequency |
| PFA | Palmdale Final Assembly |
| PFB | PayloadFeedback |
| PFB | PaYload Forward Bus |
| PFB | PositionFeedback |
| PFB | Pressure Fed Booster |
| PFC | Performance Flight Certification |
| PFC | Postflight Checklist |
| PFC | Power Factor Corrector |
| PFC | Preliminary Flight Certification |
| PFCF | Payload Flight Control Facility |
| PFCS | Primary Flight Control System |
| PFK | Payload Function Key |
| PFL | Primary Freon Loop |
| PFM | Platform |
| PFM | Pulse Frequency Modulation |
| PFP | Prograin Financial Plan |
| PFP | Programmable Function Panel |
| PFR | Portable Foot Restraint |
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