| Acronym | Meaning |
| ES | Emission Spectroscopy (technique Suffix) |
| ES | Energy Sudden (approxn. In Scattering Calcns.) |
| ES&H | Environmental Safety And Health |
| ESA | Electrostatic Self-assemblypar |
| ESA | Endangeded Species Act |
| ESA | European Space Agency |
| ESA | Electrokinetic Sonic Amplitude |
| ESA | Electron Stimulated Adsorption |
| ESA | Electrostatic Analyzer |
| ESA | Electrostatic Sector Analysis |
| ESA | Energy Sudden Approxn. (in Calcns. On Reactive Scattering) |
| ESA | Excited State Absorption |
| ESA-IRS | European Space Agency-Information Retrieval Service |
| ESAA | Earth Science Advanced Aircraft |
| ESAD | Electron-stimulated Associative Desorption |
| ESAP | Environmental Self-assessment Program |
| ESARDA | European Safeguards Research And Development Association |
| ESAT | Environmental Services Assistance Team |
| ESC | Embryonic Stem Cell |
| ESC | Endometrial Stromal Cell |
| ESC | Environmental Stress Cracking |
| ESCA | Electron Spectroscopy For Chemical Analysis |
| ESCAPE | Evaluation Of Strategies To Address Climate Change By Adapting To And Preventing Emissions |
| ESCOMPTE | (Experience Sur Site Pour Contraindre Les Modeles De Pollution Atmospherique Et De Transport D'emissions) |
| ESCORT | Error Self-compensation Reached By Tau-scrambling |
| ESCPM | Electrochemical Scanning Probe Microscopy |
| ESCR | Environmental Stress Cracking Resistance |
| ESD | Element-Specific Detector |
| ESD | Emission Standards Division |
| ESD | Environmental Services Division (US EPA) |
| ESD | Electron-stimulated Desorption |
| ESD | Electrostatic Discharge |
| ESD | Equiv. Spherical Diam. |
| ESDB | Endangered Species Database/Reach Scanlink |
| ESDI | Electron Stimulated Desorption Of Ions |
| ESDIAD | Electron Stimulated Desorption Of Ion Angular Distribution |
| ESDIM | Earth System Data And Information Management |
| ESDMS | Electron Stimulated Desorption Mass Spectrometry |
| ESDN | Electron Stimulated Desorption Of Neutrals |
| ESE | Electron Spin Echo |
| ESE | Exact Static-exchange (approxn. In Scattering Calcns.) |
| ESE | Extended-surface Electrolysis |
| ESE MO | Essential-structure-elements Molecular Orbital |
| ESEDD | Excited State Electron Density Differential Method |
| ESEEM | Electron Spin Echo Envelope Modulation |
| ESEM | Electron Spin Echo Modulation |
| ESEM | Environmental Scanning Electron Microscopy |
| ESEP | Exact Static Exchange (plus) Polarization (potential) |
| ESES | Environmental Sampling Expert System |
| ESF | Electrostatic Force (theory For Mol. Calcns.) |