| Acronym | Meaning |
| CETTP | Complex Effluent Toxicity Testing Program (US EPA) |
| CEUG | Continental Epeirogenic Uplift Granitoids |
| CEY | Conversion Electron Yield |
| CF | Cystic Fibrosis |
| CFA | Component Failure Analysis |
| CFAES | Carbon Furnace Atomic Emission Spectrometry |
| CFAST | Center For Field Analytical Studies And Technology |
| CFB | Circulating Fluidized Bed |
| CFB | Continental Flood Basalt |
| CFBC | Circulating Fluidized Bed Combustion |
| CFBR | Conventional Fluidized Bed Reactor |
| CFC | Corrosion-fatigue Cracking |
| CFCC | Continuous Fiber Ceramic Composite |
| CFCM | Continuous Feed Completely Mixed Reactor System |
| CFCMC | Continuous Fiber Ceramic Matrix Composites |
| CFD | Computational Fluid Dynamics |
| CFE | Coherent Forward Emission |
| CFE | Cold-feed Extrusion |
| CFE | Colony-forming Efficiency |
| CFEM | Combined Fates And Effects Model |
| CFF | Consistent Force Field |
| CFF-SCF-PI-C | Consistent Force Field-SCF-PI-configuration Interaction |
| CFFE | Continuous Free Flow Electrophoresis |
| CFFE | Cumulative Fissile Fuel Enrichment |
| CFFV | Clean Fuel Fleet Vehicle |
| CFGE | Crossed-field Gel Electrophoresis |
| CFGFRP | Carbon Fiber And Glass Fiber Reinforced Plastics |
| CFHH | Correlation-function Hyperspherical Harmonic (method For Calcn. Of Wave Functions) |
| CFHH-GLF | CFHH-generalized Laguerre Function |
| CFHT | Canada-France-Hawaii Telescope |
| CFM | Central Field Model |
| CFM | Charge Force Microscope |
| CFM | Charge-fluctuation Model |
| CFM | Chemical Force Microscopy |
| CFM | Contamination-free Manufacturing |
| CFM | Continued-fraction Method |
| CFM | Cubic Feet Per Minute |
| CFME | Carbon Fiber Microelectrode |
| CFMF | Cross Flow Microfiltration |
| CFMM | Continuous Fast Multipole Method (algorithm For Coulomb Interactions Among Charge Distributions) |
| CFO | Crystal Field Orbital |
| CFP | Centrifuge Facility Project |
| CFP | Coefficient Of Fractional Parentage (method In Quantum Calcns.) |
| CFPP | Cold Filter Plugging Point |
| CFR | Code Of Federal Regulations |
| CFRC | Carbon Fiber-reinforced Cement |
| CFRM | Continuous Filament Random Mat |
| CFRP | Carbon Fiber Reinforced Plastic |
| CFRT | Continuous Fiber Reinforced Thermoplastic Composite |
| CFRTP | Carbon Fiber Reinforced Thermoplastic |