| Acronym | Meaning |
| SCUVS | Stratospheric Climatology Using UV/Visible Spectroscopy |
| SCWO | Supercritical Water Oxidation |
| SD | Std. Deviation |
| SD-MBPT | Single (and) Double (substituted States) Many-body Perturbation Theory |
| SD-POE | Sigma-dependent Pi-orbital Electronegativity Model |
| SDA | Spray Drying Absorber |
| SDA | Subsurface Disposal Area |
| SDA | Strand Displacement Amplification |
| SDA | Structure-directing Agent |
| SDBS | Sodium Dodecylbenzenesulfonate |
| SDC | Samaria-doped Ceria |
| SDCI | Single And Double Excitation Configuration Interaction Model |
| SDCPA | Site-dependent Coherent Potential Approxn. |
| SDD | Silicon Drift Detector |
| SDECI | Singly And Doubly Excited Configuration Interaction |
| SDF | Spin(-unrestricted) Density Functional |
| SDF | Stromal Cell-derived Factor |
| SDFFF | Sedimentation Field Flow Fractionation (particle Analysis) |
| SDG | Signed Directed Graph (model) |
| SDGUGA | Shape-driven Graphical Unitary Group Approach |
| SDH | Succinate Dehydrogenase |
| SDI | Selective Dissemination Of Information |
| SDI | Silt Density Index |
| SDIM | Scaled Diatomics-in-molecules |
| SDIO | Strategic Defense Initiative Organization |
| SDLTS | Scanning Deep-level Transient Spectroscopy |
| SDME | Single-drop Microextraction |
| SDME | Static Mercury Drop Electrode |
| SDMM | Scanning Desorption Molecular Microscope |
| SDO | Shielded Diatomic Orbital |
| SDOSS | Sodium Dioctylsulfosuccinate |
| SDPA | 4,4'-sulfonyldiphthalic Anhydride |
| SDPM | Spin-dependent Photomodulation |
| SDQ-MBPT | Single (and) Double (and) Quadruple (substituted States) Many-body Perturbation Theory |
| SDQ-MBPT | Single-double-quadruple Excitation Many-body Perturbation Theory |
| SDR | Spin-dependent Resonance |
| SDRAM | Synchronous Dynamic Random Access Memory |
| SDRS | Surface Differential Reflectance Spectroscopy |
| SDS | Simulated Distribution System [for Water] |
| SDS | Sodium Dodecyl Sulfate |
| SDSD | Satellite Data Services Division |
| SDSL | Site-directed Spin Labeling |
| SDSR-CI | Single And Double Excitations From Single Ref. State Function-CI Method |
| SDSS | Sloan Digital Sky Survey |
| SDTQ-MBPT | Single-double-triple-quadruple Excitation (contribution) MBPT |
| SDW | Spin Density Wave |
| SDWA | Safe Drinking Water Act |
| SDY | Spin Drawn Yarn |
| SE | Standard Error |
| SE | Symmetric Eikonal (approxn. In Calcns. On Ion Scattering) |