| Acronym | Meaning |
| PHOTOSELEX | Photochemical Systematic Evolution Of Ligands By Exponential Enrichment |
| PHRED | Public Health Risk Evaluation Data |
| PHS | Public Health Service |
| PHS | Prostaglandin H Synthase |
| PHT | Pulmonary Hypertension |
| PHWR | Pressurized Heavy Water Reactor |
| PI | Plugging Index |
| PI | Pollution Index |
| PI | Polydispersity Index |
| PI3K | Phosphatidylinositol 3-kinase |
| PIA | Peaking Impulse Approxn. (for Electron-exchange Collisions) |
| PIAC | Polymer Industrial Advisory Council |
| PIAD | Plasma-ion Assisted Deposition |
| PIAMS | Photoionization Aerosol Mass Spectrometry |
| PIANO | Paraffin |
| PIAS | Photon-counting Image Acquisition System |
| PIB | Potential Induced Breathing (model In Electronic-structure Studies In Superconductors) |
| PIC | Public Information Center |
| PIC | Products Of Incomplete Combustion |
| PICA | Picosecond Imaging Circuit Analysis |
| PICA | Polymerization-induced Colloid Aggregation |
| PICI | Positive-ion Chemical Ionization |
| PICLS | Photoionization Controlled-loss Spectroscopy |
| PICP | Carboxyterminal Propeptide Of Type I Procollagen |
| PICT | Pollution-induced Community Tolerance |
| PID | Photoionization Detector (gas Chromatography) |
| PIDAS | Portable Instantaneous Display And Analysis Spectrometer |
| PIDIE | Plutonium Isotopic Detn. Intercomparison Exercise |
| PIERS | Polarized Infrared External Reflection Spectroscopy |
| PIES | Pollution Prevention Information Exchange System |
| PIES | Partial Integration Exterior Scaling (in Calcns. On Resonance Positions And Lifetimes |
| PIES | Penning Ionization Electron Spectroscopy |
| PIET | Photoinduced Intramolecular Electron Transfer |
| PIF | Photochemically-induced Fluorescence |
| PIGE | Proton Induced Gamma-ray Emission |
| PIGS | Pesticides In Groundwater Strategy |
| PIHMC | Path Integral Hybrid Monte Carlo |
| PIII | Plasma Immersion Ion Implantation |
| PILA | Publishers International Linking Association |
| PILC | Pillar Interlayered Clays |
| PIM | Powder Injection Molding |
| PIMA | Polyisocyanurate Insulation Manufacturers Association |
| PIMBE | Plasma-induced Molecular-beam Epitaxy |
| PIMC | Path-integral Monte-Carlo |
| PIMD | Path Integral Molecular Dynamics |
| PIMIA | Potentiometric Ionophore-modulation Immunoassay |
| PIMS | Process Information Management System |
| PIN | Pesticide Information Network |
| PINA | Paraffins |
| PINN | Proposed International Nonproprietary Names (for Drugs) |