| Acronym | Meaning |
| NRPS | Nonribosomal Peptide Synthetase |
| NRRA | Nuclear Resonant Reaction Analysis |
| NRT | National Response Team |
| NRTI | Nucleoside Reverse Transcriptase Inhibitor |
| NRTL | Non-random Two Liquid |
| NRW | Null Reflecting Water |
| NSAID | Non-steroidal Anti-inflammatory Drug |
| NSC | National Safety Council |
| NSCEP | National Service Center For Environmental Publications |
| NSCF | Non-self-consistent Field |
| NSCLC | Non-small Cell Lung Cancer |
| NSCP | North Sea Community Program |
| NSCR | Nonselective Catalytic Reduction |
| NSCSS | Noise-suppressing Capillary Separation System |
| NSDL | National Science Digital Library |
| NSDWR | National Secondary Drinking Water Regulations |
| NSE | Neuron-specific Enolase |
| NSE | Neutron Spin Echo |
| NSE | Nonlinear Schroedinger Equation |
| NSERC | Natural Sciences And Engineering Research Council (Canada) |
| NSES | National Science Education Standards |
| NSF | National Sanitation Foundation |
| NSF | National Science Foundation |
| NSF | Near-surface Fractionated (mantle) |
| NSH | Normalized Spherical Harmonic (hamiltonian) |
| NSIDC | National Snow And Ice Data Center (University Of Colorado) |
| NSLS | National Synchrotron Light Source |
| NSO | Natural Spin Orbitals |
| NSOM | Near-field Scanning Optical Microscopy |
| NSP | North Sea Project |
| NSP | Non-starch Polysaccharide |
| NSPS | New Source Performance Standards |
| NSR | New Source Review |
| NSR | Nitrile-silicone Rubber |
| NSR | Normalized Stoichiometric Ratio |
| NSRDS | National Standard Reference Data System |
| NSS | National Stream Survey (USA) |
| NSSDC | National Space Science Data Center |
| NSSN | National Standards Systems Network |
| NSSS | National Sewage Sludge Survey |
| NSSS | Nuclear Steam Supply System |
| NSSTC | National Space Science And Technology Center |
| NSTA | National Science Teachers Association |
| NSTC | National Science And Technology Council |
| NSTF | North Sea Task Force (multinational Organization) |
| NSTL | Near Surface Transition Layer |
| NSTX | National Spherical Torus Experiment |
| NSWMA | National Solid Wastes Management Association |
| NSWS | National Surface Water Survey |
| NTA | Nitrilotriacetic Acid |