| Acronym | Meaning |
 | LRMA | Laser Raman Microanalysis |
| LRMS | Low Resolution Mass Spectrometry |
| LRO | Long Range Order |
| LRR | Leucine-rich Repeat |
| LRS | Laser Raman Spectroscopy |
| LRS | Laser Resonant Shadowgraphy |
| LRT | Long Range Transport |
| LRTAP | Long-range Transboundary Air Pollution |
| LRTBAP | Long-range Trans-boundary Air Pollution |
| LRTI | Lower Respiratory Tract Infection |
| LSA | Linear Superposition Approximation |
| LSA | Local Space Approximation |
| LSASV | Linear Sweep Anodic Stripping Voltammetry |
| LSC | Liq. Scintillation Counting |
| LSC | Luminescent Solar Concentrator |
| LSCM | Laser Scanning Confocal Microscopy |
| LSD | Lysergic Acid Diethylamide |
| LSD-GX | Local Spin Density Functional-generalized Exchange |
| LSD-GX-CSEP | LSD-GX-with Correction Of Statistical Exchange Potential |
| LSD-GX-SIC | LSD-GX-with Generalized Exchange-self-interaction Corrected |
| LSD-SCF | Local Superdirect-self-consistent Field |
| LSDA | Local Spin Density Approximation |
| LSDC | Local Spin Density Correlation (functional) |
| LSDF | Local Spin Density Functional |
| LSDFT | Local Spin Density Functional Theory |
| LSDSIC | Local-spin-density Self-interaction-correction Approxn. (in Total Energy Calcns. For Atoms) |
| LSDX | Local-spin-density (with Exact) Exchange |
| LSDXC | Local-spin-density-exchange-correlation (for Mol. Property) |
| LSDXS | Local-spin-density (with) Screened Exchange |
| LSDXS-SIC | Local-spin-density (with) Screened Exchange (and) Self-interactiond Correction |
| LSE | Liquid/solid Extraction |
| LSER | Linear Solvation Energy Relationship |
| LSF | Laser-saturated Fluorescence |
| LSI | Large-scale Integration |
| LSIMS | Liquid Secondary Ion Mass Spectrometry |
| LSIRD | Lunar Scout Infrared Detector |
| LSM | Land Surface Model |
| LSM | Laser Scanning Microscopy |
| LSM | Laser Surface Melting |
| LSM | Layered Synthetic Microstructure |
| LSM | Liquid Surfactant Membrane |
| LSM | Loop Sampling Mode |
| LSMS | Laser Scan Mass Spectrometry |
| LSND | Liquid Scintillator Neutrino Detector |
| LSNMS | Laser Secondary Neutral Mass Spectroscopy |
| LSP | Liquid-stabilized Plasma |
| LSPR | Localized Surface Plasmon Resonance |
| LSR | Lanthanide Shift Reagent |
| LSR | Liquid Silicone Rubber |
| LSRA | Least-squares Regression Analysis |
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