| Acronym | Meaning |
| LOTOS | Long Term Ozone Simulation |
| LOVA | Lowest-order Variational Approxn. (for Electron-phonon Interactions In Metals) |
| LOX | Liquid Oxygen |
| LOXJET | Liq. Oxygen Torch System |
| LPA | Linear Polyacrylamide |
| LPA | Linearized Propagator Approximation |
| LPA | Lipoprotein A |
| LPA | Local Plasma Approxn. (in Calcns. Of Stopping Powers For Ions By Films) |
| LPA | Low Profile Additive [in Plastic Composites] |
| LPA | Lysophosphatidic Acid |
| LPAS | Laser Photoacoustic Spectroscopy |
| LPAS | Long Pathlength Absorbance Spectroscopy |
| LPC | Light Paraffin Conversion |
| LPCVD | Low Pressure Chemical Vapor Deposition |
| LPE | Liquid-phase Epitaxy |
| LPED | Low-pressure Electric Discharge |
| LPEE | Liquid Phase Electroepitaxy |
| LPFF | Laser Photolysis Fragment Fluorescence |
| LPFG | Long-period Fiber Grating |
| LPG | Liquefied Petroleum Gas |
| LPGD | Low-pressure Gas Discharge |
| LPIC | Low Pressure Ion Chromatography |
| LPIM | Low-pressure Injection Molding |
| LPIN | Lipoprotein Ice Nucleator |
| LPL | Lipoprotein Lipase |
| LPLC | Lift Plus Lift Cruise |
| LPLC | Low Pressure Liquid Chromatography |
| LPM | Liters Per Minute |
| LPMA | Laser-probe Microanalysis |
| LPME | Liquid-phase Microextraction |
| LPO | Lipid Peroxidation |
| LPP | Laser-produced Plasma |
| LPPS | Low-pressure Plasma Spraying |
| LPS | Laser Plasma Spectroscopy |
| LPS | Liquid-phase Sintering |
| LPUMP | L-fold (spin) Projected Unrestricted Moeller-Plesset |
| LPVD | Laser Physical Vapor Deposition |
| LPWN | Low Power Wireless Network |
| LQG | Linear Quadratic Gaussian |
| LQG | Loop Quantum Gravity |
| LQR | Linear Quadratic Regulator |
| LR-SCF | Low-rank SCF |
| LRAD | Long-range Alpha Detection |
| LRAT | Lecithin-retinol Acyltransferase |
| LRAT | Long-range Atmospheric Transport |
| LRCI | Low-rank Configuration Interaction |
| LREE | Light Rare Earth Element(s) |
| LRET | Luminescence Resonance Energy Transfer |
| LRFDCD | Lifetime-resolved Fluorescence-detected Circular Dichroism |
| LRM | Laboratory Reference Material |