| Acronym | Meaning |
| IUAM | Independent United Atom Model (in Positron Scattering By Mols.) |
| IUAPPA | International Union Of Air Pollution Prevention Associations |
| IUBMB | International Union Of Biochemistry And Molecular Biology |
| IUBS | International Union Of Biological Sciences |
| IUCHF | Improved Uncoupled Hartree Fock |
| IUCLID | International Uniform ChemicaL Information Database |
| IUCN | International Union For Conservation Of Nature And Natural Resources |
| IUCR | International Union Of Crystallography |
| IUE | International Ultraviolet Explorer |
| IUGG | International Union Of Geodesy And Geophysics |
| IUGS | International Union Of Geological Sciences |
| IUMS | International Union Of Microbiological Societies |
| IUPAB | International Union Of Pure And Applied Biophysics |
| IUPAC | International Union Of Pure And Applied Chemistry |
| IUPAP | International Union Of Pure And Applied Physics |
| IUPHAR | International Union Of Pharmacology |
| IUPPA | The International Union Of Air Pollution Prevention Associations |
| IUTOX | International Union Of Toxicology |
| IUVSTA | International Union Of Vacuum Science |
| IVA | Intravehicular Activity (related To Spacecraft) |
| IVAP | Intimate Valence Alternation Pairs (bonding Model In Electronic Structure Calcns.) |
| IVC | In Vitro Culture |
| IVC | Inferior Vena Cava |
| IVCT | Intervalence Charge Transfer |
| IVF | In Vitro Fertilization |
| IVGTT | Intravenous Glucose Tolerance Test |
| IVM | In Vitro Maturation |
| IVNAA | In Vivo Neutron Activation Analysis |
| IVO | Improved Virtual Orbital |
| IVR | Intramolecular Vibrational Energy Redistribution |
| IWEM | Institution Of Water And Environmental Management |
| IWG | International Working Group |
| IWIC | International Waste Identification Code |
| IWKB | Iterated Wentzel-Kramers-Brillouin |
| IWMIS | INEL Industrial Waste Management Information System |
| IWOP | Integration Within (an Ordered Product Of) Operators |
| IWRA | International Water Resources Association (USA) |
| IWS | Ionizing Wet Scrubber |
| IWSA | International Water Supply Association |
| IWW | Industrial Wastewater |
| IX | Ion Exchange |
| IXS | International XAFS Society |
| IZA | International Zeolite Association |
| J(Z)CCS | J(z) Conserving Centrifugal Sudden Approximation (in Molecular Collisions |
| J(Z)CCS | J(z)-conserving Coupled States Method (for Rotationally Inelastic Atom-molecule Collisions |
| JAERI | Japanese Atomic Energy Research Institute |
| JAICI | Japan Association For International Chemical Information |
| JAIE | Japan Association Of Ion Exchange |
| JAK | Janus Kinase |
| JAM | Junctional Adhesion Molecule |