| Acronym | Meaning |
| GREAT-ER | Geog.-referenced Regional Exposure Assessment Tools For European Rivers |
| GRF | Growth Hormone Releasing Factor |
| GRGL | Groundwater Residue Guidance Level |
| GRHF | Generalized Restricted Hartree-Fock |
| GRI | Gas Research Institute |
| GRI | Geosynthetics Research Institute (Drexel University |
| GRID | Global Resources Information Database |
| GRIDS | Geographic Resources Information And Data System |
| GRIMM | Global/Regional Interhemispheric Mercury Model |
| GRIN | Graded Index |
| GRIN | Gradient Refractive Index |
| GRINDOL | Ghost (and) Rydberg INDO |
| GRINSCH | Graded-index Separate Confinement Heterostructure |
| GRIP | Greenland Ice Core Project |
| GRK | G Protein Coupled Receptor Kinase |
| GRM | Geopotential Research Mission (USA Satellite) |
| GRNN | Generalized Regression Neural Network |
| GRO | Gasoline-range Organics |
| GRP | Glass Reinforced Plastic |
| GRP | Gastrin-releasing Peptide |
| GRPA | Generalized Random-phase Approximation |
| GRRR | Graduated Response For Risk Reduction |
| GRVB | Generalized Resonating Valence Bond |
| GRWA | Generalized Rotating-wave Approxn. (in Energy Level Calcns.) |
| GS | Gelius-Siegbahn (MO Approxn.) |
| GSA | General Services Administration |
| GSA | Geological Society Of America |
| GSA | Generalized Sudden Approximation |
| GSA | Generator-state Approach (in Many-body Quantum Theory) |
| GSAC | Generalized Symmetry Adapted Cluster (theory) |
| GSAM | Generalized Standard Addition Method |
| GSAS | Generalized Structure And Anal. Software |
| GSC | Geological Survey Of Canada |
| GSCF | Generalized Self-consistent Field |
| GSCRF | Generalized Self-consistent Reaction Field |
| GSD | Geometric Std. Deviation |
| GSD | Glycogen Storage Disease |
| GSFC | Goddard Space Flight Center (of NOAA |
| GSGG | Gallium Scandium Gadolinium Garnet |
| GSH-PX | Glutathione Peroxidase |
| GSHV | Ground Squirrel Hepatitis Virus |
| GSI | Gesellschaft Fuer Schwerionenforschung |
| GSI | Gonadosomatic Index |
| GSJ | Geological Survey Of Japan |
| GSK | Glycogen Synthase Kinase |
| GSM | Global System For Mobile Telecommunications |
| GSMBE | Gas Source Molecular-beam Epitaxy |
| GSMO | Ground-state Molecular Orbital |
| GSMT | Giant Segmented Mirror Telescope |
| GSNO | Ground-state Natural Orbital |