| Acronym | Meaning |
 | GIRM | Generalized Internal Reference Method |
| GIRMS | Gas Isotope Ratio Mass Spectrometry |
| GIS | Geographical Information System |
| GIS | Gas Insulated Switchgear |
| GISAXS | Grazing Incidence Small Angle X-ray Scattering |
| GISNET | Geographic Information Systems Bulletin Board |
| GISP | Greenland Ice Sheet Precipitation |
| GISPRI | Global Industrial And Social Progress Institute (Japan) |
| GISS | Goddard Institute For Space Studies |
| GIST | Gastrointestinal Stromal Tumor |
| GIT | Gastrointestinal Tract |
| GITR | Glucocorticoid-induced Tumor Necrosis Factor Receptor |
| GITT | Galvanostatic Intermittent Titration Technique |
| GITXRF | Glancing Incidence And Takeoff X-ray Fluorescence |
| GIWA | Global International Waters Assessment |
| GIXA | Glancing-incidence X-ray Analysis |
| GIXAS | Grazing Incidence X-ray Absorption Spectroscopy |
| GIXD | Grazing Incidence X-ray Diffraction |
| GIXR | Grazing Incidence X-ray Reflectivity |
| GIXRD | Grazing Incidence X-ray Diffraction |
| GIXS | Grazing Incidence X-ray Scattering |
| GJIC | Gap Junctional Intercellular Communication |
| GKS | Gaspar-Kohn-Sham (potential For Exchange And Correlation In Band Structure Calcns.) |
| GLAD | Great Lakes Atmospheric Deposition |
| GLAD | Glancing Angle Deposition |
| GLAO | Generalized Localized Ao |
| GLAS | Geoscience Laser Altimeter System |
| GLAST | Gamma-ray Large Area Space Telescope |
| GLC | Ground Level Concentration |
| GLC | Gas Liquid Chromatography |
| GLE | Generalized Langevin Equation |
| GLEAMS | Groundwater Loading Effects Of Agricultural Management Systems |
| GLERL | Great Lakes Environmental Research Laboratory |
| GLF | Gaussian Lobe Function |
| GLF | Generalized Laguerre Function |
| GLIMMER | Gene Locator And Interpolated Markov Modeler |
| GLIMPSE | Galactic Legacy Infrared Mid-Plane Survey Extraordinaire |
| GLIS | Global Land Information System |
| GLISP | Great Lakes International Surveillance Plan |
| GLM | General Linear Model |
| GLNPO | Great Lakes National Program Office |
| GLO | Gaussian Lobe Orbital |
| GLOBE | Global Learning And Observations To Benefit The Environment |
| GLOMAC | Global Modeling Of Atmospheric Chemistry |
| GLORIA | Geological LOng Range Inclined Asdic |
| GLORIA | Gold-labeled, Optically Read, Rapid Immunoassay |
| GLOSS | Global Sea Level Observing System (of IOC) |
| GLP | Good Laboratory Practices (US FDA) |
| GLP | Great Lakes Precipitation |
| GLP | Glucagon-like Peptide |
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