| Acronym | Meaning |
 | IFO | Identified Flying Object (see Also UFO) |
| IFOR | UN Implementation Force -Institute For Operations Research - International Fellowship Of Reconciliation |
| IFOV | Instantaneous Field Of View |
| IFPI | International Federation Of Phonographic Industries |
| IFR | Instrument Flight Rules |
| IFRB | International Frequency Registration Board |
| IFV | Infantry Fighting Vehicle |
| IG | Inspector General |
| IG | Igbo Language (ISO 639-1 Code) |
| IGS | International Ground Station |
| IGY | International Geophysical Year |
| IHH | Idiopathic Hypogonadotropic Hypogonadism |
| IHO | International Hydrographic Organization |
| IHR | Institute For Historical Review |
| IHS | Institut Des Hautes ?tudes Scientifiques (French |
| II | Sichuan Yi Language (ISO 639-1 Code) |
| II | Two (in Roman Numerals) |
| IICA | Inter-American Institute For Cooperation On Agriculture |
| IIE | Innovative Interstellar Explorer |
| III | Sichuan Yi Language (ISO 639-2 Code) |
| III | Three (in Roman Numerals) |
| IIRC | If I Recall/Remember Correctly |
| IISS | International Institute For Strategic Studies |
| IIT | Illinois Institute Of Technology - Indian Institutes Of Technology - Indiana Institute Of Technology |
| IJN | Imperial Japanese Navy (World War II) |
| IJWP | Interim Joint Warfare Publication |
| IK | Inupiaq Language (ISO 639-1 Code) |
| IKEA | Ingvar Kamprad (the Company's Founder) |
| IKU | Inuktitut Language (ISO 639-2 Code) |
| IL | Illinois (postal Symbol) - Israel (ISO 3166 Digram) |
| ILC | International Law Commission - International Linear Collider |
| ILDS | Improved Landmine Detection System |
| ILE | Interlingue Language (ISO 639-2 Code) |
| ILO | International Labour Organization |
| ILRI | International Livestock Research Institute |
| ILS | Israeli Shekel (ISO 4217 Currency Code) |
| ILY | I Love You [pronounced ILL-LEE] |
| IM | Isle Of Man (FIPS 10-4 Territory Code) -Instant Message (internet Speech) |
| IMA | Intermediate Maintenance Activity |
| IMBD | International Migratory Bird Day |
| IMDB | Internet Movie Database |
| IMF | International Monetary Fund |
| IMHO | In My Humble Opinion |
| IML | International Mister Leather |
| IMLAST | International Movement For Leisure Activities In Science And Technology - See MILSET |
| IMNSHO | In My Not So Humble Opinion |
| IMO | In My Opinion - International Maritime Organization |
| IMPAC | International Merchant Purchase Authorization Card |
| IMPACT | International Medical Products Anti-Counterfeiting Taskforce |
| IMPATT | IMPact Avalanche Transit Time Diode |
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