| Acronym | Meaning |
 | EBW | Electron Beam Welding |
| EBW | Exploding BridgeWire |
| EC | Ecuador (ISO 3166 Digram; FIPS 10-4 Country Code) -Electronic Combat - European Community (see EEC) -Exacoulomb |
| ECB | European Central Bank - England (and Wales) Cricket Board |
| ECBR | European Coalition For Biomedical Research |
| ECCM | Electronic Counter-Counter-Measures |
| ECHO | Each Community Helps Others (EPA Programme) - Educational Concerns For Hunger Organization - European Commission Host Organization - European Commission Humanitarian Aid Office -Exchange Clearing House - Expanded Characteristic Option -Explanatory Coheren |
| ECHR | European Convention On Human Rights |
| ECJ | European Court Of Justice |
| ECL | Emitter Coupled Logic (electronics) |
| ECM | Electronic Counter-Measures - Enterprise Content Management |
| ECOMMHR | European Commission On Human Rights |
| ECS | Emergency Contact System - Enhanced Chip Set (computing) - EOSDIS Core System - Extended Chip Set (computing) |
| ECSC | European Coal And Steel Community (distant Ancestor Of The EU) |
| ECT | ElectroConvulsive Therapy |
| ECTHR | European Court Of Human Rights |
| ECU | Ecuador (ISO 3166 Trigram) -European Currency Unit (ancestor Of The Euro) |
| ECW | Eastern Championship Wrestling - Extreme Championship Wrestling |
| EDA | European Defence Agency |
| EDAC | Error Detection And Correction |
| EDC | DAAC -EROS Data Center Distributed Active Archive Center |
| EDCS | Environmental Data Coding Specification |
| EDECSIM | Extended Directed Energy Combat Simulation |
| EDH | Eastman Dental Hospital |
| EDS | Electronic Data Systems - Electronic Differential System |
| EDSA | Epifanio De Los Santos Avenue (a Major Thoroughfare In Manila With Great Significance To Post-1980 Philippines History) |
| EDT | Eastern Daylight Saving Time (UTC-4 Hours) |
| EDTA | Electric Drive Transportation Association -EthyleneDiamineTetraAcetic Acid |
| EE | Estonia (ISO 3166 Digram) -Electrical Engineering - Electrical Engineer |
| EE | Ewe Language (ISO 639-1 Code) |
| EEC | European Economic Community (predecessor Of The EU) |
| EEG | ElectroEncephaloGram |
| EEK | Estonian Kroon (ISO 4217 Currency Code) |
| EEZ | Economic Exclusion Zone Or Exclusive Economic Zone |
| EF | Entry Foyer |
| EF | Exafarad |
| EFF | Electronic Frontier Foundation |
| EFL | English As A Foreign Language |
| EFOA | European Fuel Oxygenates Association |
| EFSA | European Food Safety Authority |
| EFT | Electronic Fund Transfer |
| EFV | Expeditionary Fighting Vehicle |
| EG | Egypt (ISO 3166 Digram; FIPS 10-4 Country Code) |
| EGBUS | External Genitalia |
| EGCG | EpiGalloCatechin-3-Gallate |
| EGIS | Erieye Ground Interface Segment |
| EGP | Egyptian Pound (ISO 4217 Currency Code) |
| EGRET | Energetic Gamma-Ray Experiment Telescope |
| EGY | Egypt (ISO 3166 Trigram) |
| EH | Exahenry - Western Sahara (ISO 3166 Digram) |
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