| Acronym | Meaning |
 | TO | Operations Management (TS) |
| TO | Takeoff |
| TO | Task Order |
| TO | Technical Order |
| TOC | Test Operations Center |
| TOC | Test Operations Change |
| TOC | Total Organic Carbon |
| TOF | Test Operations Facility |
| TOG | Toggle |
| TOI | Transfer Orbit Insertion |
| TOL | Tolerance |
| TOO | Test Operations Order |
| TOO | Threshold Of Odor |
| TOP | Technical Operating Procedure |
| TOPS | Transistorized Operational Phone System |
| TOS | Test Operating System |
| TOT | Total |
| TOW | Tank And Orbiter Weight |
| TP | Test Point |
| TP | Test Port |
| TP | Test Procedure |
| TP | Time To Perigee |
| TP | Training Plan |
| TP | Transition Period (T.P. Preferred) |
| TP | True Position |
| TP | Turbo Pump |
| TP | Type |
| TP&C | Thermal Protection And Control |
| TPA | Test Preparation Area |
| TPAD | Trunnion Pin Attachment Device |
| TPC | Telemetry Preprocessor Computer |
| TPDS | Test Procedures DeveloPment System |
| TPE | Test Project Engineer |
| TPF | Terminal Phase Finalization (Braking) |
| TPF | Terminal Phase Finish |
| TPF | Transfer Phase Final |
| TPF | Tug Processing Facility |
| TPI | Terminal Phase Initiation |
| TPM | Technical Performance Measurement (System) |
| TPM | Terminal Phase Maneuver |
| TPM | Terminal Phase Midcourse |
| TPM | Transfer Phase Midcourse |
| TPM | 1Terminal Phase Midcourse #1 |
| TPM2 | Terminal Phase Midcourse #2 |
| TPO | Test Program Out@ine |
| TPR | Teleprinter |
| TPR | Test ProblemReport |
| TPS | Thermal Protection System (SR[3 |
| TPS | Test Preparation Sheet |
| TPS | Thermal Protection Subsystem |
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