| Acronym | Meaning |
 | SUTAGS | Shuttle Uplink Text And Graphics Scanner |
| SV | Safety Valve |
| SV | Selenoid Valve |
| SV | Shuttle Vehicle |
| SV | Space Vehicle |
| SV | State Vector |
| SVA&C | Shuttle Vehicle Assembly And Checkout |
| SVAB | Shuttle Vehicle Assembly Building |
| SVAC | Shuttle Vehicle Assembly And Checkout (Facility) |
| SVAFB | South Vandenberg Air Force Base |
| SVB | Shuttle Vehicle Booster |
| SVB | Space Vehicle Booster |
| SVC | Supervisor Call |
| SVDS | Space Vehicle Dynamic Simulator |
| SVO | Space Vehicle Operations (KSC Dir.) |
| SVRR | Software Verifir-ation Readiness Review |
| SVS | Suit Ventilation System |
| SW | Sea Water |
| SW | Short Wave |
| SW | Software (SFTWE Preferred) |
| SW | Solar Wing |
| SW | Status Word |
| SW | Switcher (Switch) |
| SW/PM | System Management/Performance Monitor |
| SWA | Support Work Authorization |
| SWAA | SPacelab Window Adapte |
| SWAD | Subdivision Of Work Authorization Document |
| SWAT | Stress Wave Analysis Technique |
| SWG | Software Working Group |
| SWOB | Salaries |
| SWP | Safe Working Pressure |
| SWR | Standing Wave Ratio |
| SWS | Switch Scan |
| SWT | Sextant |
| SWT | Supersonic Wind Tunnel |
| SXT | Sextant |
| SY | Shoulder Yaw |
| SY | System |
| SYM | Symbol |
| SYMM | Symmetrical |
| SYN | Synchronous |
| SYN | Synthetic |
| SYNC | Synchronize |
| SYNCOM | Hughes Spin Stabilized Spacecraft |
| SYNCOM | Synchronous Communication Satellite (Hughes) |
| SYS | System |
| SYSTRAN | Systems Analysis Translator |
| T | Transformation (Matrix) |
| T | Superscript) |
| T | Talk/Monitor |
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