| Acronym | Meaning |
| R | Roll |
| R | Yaw Rankine Rate |
| R | LEO Request Liaison Engineering Order |
| R | LSS Regenerative Life Support System |
| R | BARRadius Vector Axis |
| R | DOTRange Rate To Target |
| R | ETSReconfigurable Electrical Test Stand |
| R | ETSReconfiguration Electrical Test Stand |
| R | IMPMinimum Range To Avoid Plum Impingement |
| R&CC | Recorder And Communication Control |
| R&D | Research And Development |
| R&DO | Research And Development Operations (MSFC) |
| R&OA | Reliability And Quality Assurance |
| R&P | Reserve And Process |
| R&PM | Research And Program Management |
| R&R | Remove And Replace |
| R&R | Rendezvous And Recovery |
| R&Z | Range And Zero |
| R-T | Resistance Test |
| R/A | Radar Altimeter |
| R/C | Radio Command |
| R/C | Rate Of Climb |
| R/C | Remote Control |
| R/D | Rate Of Descent |
| R/E | Reentry |
| R/I | Receiving Inspection |
| R/L | Rate/Limited |
| R/L | Remote/Local |
| R/O | Rollout |
| R/S | Range Safety |
| R/S | RedundantSet |
| R/T | Real Time |
| R/T | Receiver/Transmitter |
| R/W | Read/Write |
| R/W | Runway |
| RA | Radar Altimeter |
| RA | Radar Altimeter (R/A Preferred) |
| RA | Radium |
| RA | Range Area |
| RA | Right Aft |
| RA | Right Ascension |
| RAAB | Remote Amplifier Acquisition And Advisory Box |
| RAAB | Remote Amplifier And Adoption Box |
| RAAB | Remote Application And Advisory Box |
| RAC | ReliabilitY Action Center |
| RACS | Rotation Axis Coordin |
| RACS | Remote Automatic Calibration System |
| RACU | Remote Acquisition And Command Unit |
| RAD | Radar |
| RAD | Radian |