| Acronym | Meaning |
| DIDA | Diisodecyl Adipate |
| DIDA | Direct Isotope Dilution Analysis |
| DIDG | Diisodecyl Glutarate |
| DIDMOAD | Diabetes Insipidus |
| DIDP | Diisodecyl Phthalate |
| DIERS | Design Institute For Emergency Relief Systems (AIChE) |
| DIET | Desorption Induced By Electronic Transitions |
| DIG | Diffuse Ionized Gas |
| DIGE | Deuteron Induced Gamma-ray Emission |
| DIGGER | Discrete Isolation From Gradient-governed Elimination Of Resonances |
| DIGIT | Deep Infrared Galaxy Imaging Telescope |
| DIGM | Diffusion Induced Grain Boundary Migration |
| DIGS | Disorder-induced Gap State |
| DIHEN | Direct Injection High Efficiency Nebulizer |
| DIIMFP | Differential Inverse Inelastic Mean Free Path |
| DIIS | Direct Inversion In The Iterative Space |
| DIM | Dissolved Inorganic Matter |
| DIM-3C | Diatomics-in-mols. Method Including 3-center Terms (integrals) |
| DIMET | Desorption Induced By Multiple Electronic Transitions |
| DIMOX | Direct Metal Oxidn. |
| DIMP | Diisopropyl Methylphosphonate |
| DIMPP | Differential Integrated Multiple Pulse Polarography |
| DIMZO | Diatomics-in-molecules Zero-overlap |
| DIN | Deutsche Industrie-Norm (German Industrial Standard) |
| DIN | Direct Injection Nebulizer |
| DIN | Dissolved Inorganic Nitrogen |
| DINA | Diisononyl Adipate |
| DINP | Diisononyl Phthalate |
| DIOA | Diisooctyl Adipate |
| DIOF | Diisooctyl Fumarate |
| DIOP | Diisooctyl Phthalate |
| DIOS | Desorption-ionization On Silicon |
| DIOS | Diisooctyl Sebacate |
| DIOS | Direct Iron Ore Smelting |
| DIOZ | Diisooctyl Azelate |
| DIP | Dissolved Inorganic Phosphorus |
| DIP | Document Image Processing |
| DIPE | Diisopropyl Ether |
| DIPP | Deformed Inverse-power Potential |
| DIPPR | Design Institute For Physical Property Data |
| DIPSI | Direct Implicit Plasma Surface Interactions (computer Program) |
| DIR | Diffusion Induced Recrystn. |
| DIRBE | Diffuse IR Background Experiment |
| DIRLD | Dynamic Infrared Linear Dichroism |
| DIS | Deep Inelastic Scattering |
| DISC | Death-inducing Signaling Complex |
| DISEP | Difference Integrated Spatial Electron Populations |
| DISI | Direct-injection Spark-ignition |
| DIT | Diffusive Interfacial Transport |
| DIU | Data Information Unit (of WOCE Data System) |