| Acronym | Meaning |
| DGB | Distributed Gaussian Basis (mol. Wave Function) |
| DGD | Decision Guidance Documents |
| DGE | Differential Gene Expression |
| DGEBA | Diglycidyl Ether Of Bisphenol A |
| DGEBF | Diglycidyl Ether Of Bisphenol F |
| DGGE | Denaturing-gradient Gel Electrophoresis |
| DGME | Diethylene Glycol Monomethyl Ether |
| DGNAA | Delayed Gamma-ray Neutron Activation Analysis |
| DGS | DiGeorge Syndrome |
| DGT | Diffusive Gradients In Thin Films |
| DH | Dortmund-Hoerder (German Vacuum Steel Refining) |
| DHA | Docosahexaenoic Acid |
| DHB | 2,4-dihydroxybenzoic Acid |
| DHBT | Double Heterojunction Bipolar Transistor |
| DHCP | Double Hexagonal Close Packedpar |
| DHF | Dengue Hemorrhagic Fever |
| DHF | Decoupled Hartree-Fock |
| DHF | Derivative Hartree-Fock (quantum Theory In Calcns. On Mols.) |
| DHFR | Dihydrofolate Reductase |
| DHHS | Department Of Health And Human Services |
| DHMS | Dense Hydrous Magnesium Silicates |
| DHOT | Double-heterojunction Optical Thyristor |
| DHP | Diheptyl Phthalate |
| DHPLC | Denaturing High-performance Liquid Chromatography |
| DHS | Department Of Homeland Securitypar |
| DHS | Department Of Health Services |
| DHS | Double Heterostructure |
| DHS | Dynamic Headspace |
| DHT | Down-hole Temperature |
| DHXP | Dihexyl Phthalate |
| DI | Differentiation Index |
| DI | Direct Injection (engine; Diesel) |
| DIA | Drug Information Association |
| DIAL | Differential Absorption Lidar (laser Radar Sensing) |
| DIANA | Detection Of Immobilized Amplified Nucleic Acids |
| DIANE | Direct Information Access Network For Europe |
| DIB | Dibutyl Chlorendate |
| DIB | Diffuse Interstellar Band |
| DIBA | Diisobutyl Adipate |
| DIBAH | Diisobutylaluminum Hydride |
| DIBAL | Diisobutylaluminum Hydride |
| DIBL | Drain Induced Barrier Lowering |
| DIBP | Diisobutyl Phthalate |
| DIBS | Dual Ion Beam Sputtering |
| DIC | Differential Interference Contrast |
| DIC | Disseminated Intravascular Coagulation |
| DIC | Dissolved Inorganic Carbon |
| DICD | Dispersion-induced Circular Dichroism |
| DICE | Dynamic Integrated Climate-economy Model |
| DID | Dipole-induced-dipole (in Mol. Polarizabilities Calcn.) |