| Acronym | Meaning |
| CFS | Chemical Fixation And Solidification (of Hazardous Wastes) |
| CFS | Chronic Fatigue Syndrome |
| CFS | Coherent Forward Scattering |
| CFS | Continuous Flow System |
| CFS | Cubic Feet Per Second |
| CFSAN | Center For Food Safety & Applied Nutrition |
| CFSE | Crystal Field Stabilization Energy |
| CFSL | Cavitation-field Sonoluminescence |
| CFSO | Crystal Field Surface Orbital |
| CFSRM | Coherent Forward Scattering Resonance Monochromator |
| CFSS | Constant-final-state Spectroscopy |
| CFSTI | Clearinghouse For Federal Scientific And Technical Information |
| CFSTR | Continuous Flow Stirred Tank Reactor |
| CFT | Conformal Field Theory |
| CFTA | Cosmetic, Toiletry, And Fragrance Association |
| CFTR | Cystic Fibrosis Transmembrane Conductance Regulator |
| CFU | Colony Forming Unit (for Bacteria Counting In Water Disinfection) |
| CGA | Compressed Gas Association |
| CGA | Chromogranin A |
| CGA | Colloidal Gas Aphron |
| CGAP | Cancer Genome Anatomy Project |
| CGC | Capillary Gas Chromatography |
| CGC | Cerebellar Granule Cells |
| CGC | Constrained Geometry Catalyst |
| CGCC | Coal Gasification/combined Cycle |
| CGCG | Catalog Of Galaxies And Clusters Of Galaxies |
| CGCG | Central Giant Cell Granuloma |
| CGCP | Canadian Global Change Program |
| CGCT | Constrained Geometry Catalyst Technology [polymerization] |
| CGDE | Contact Glow Discharge Electrolysis |
| CGDN | Canadian Genetic Diseases Network |
| CGE | Capillary Gel Electrophoresis |
| CGF | Coulomb Green Function |
| CGH | Comparative Genomic Hybridization |
| CGHE | Carrier Gas Hot Extraction |
| CGI | Clinical Global Impression |
| CGI | Combustible Gas Indicator |
| CGI | Common Gateway Interface (web Scripting Tool) |
| CGIAR | Consultative Group On International Agricultural Research |
| CGL | Comprehensive General Liability Policy |
| CGMP | Cyclic Guanosine Monophosphate |
| CGO | Configuration Generating Orbital (a Type Of MO) |
| CGPS | Canadian Galactic Plane Survey |
| CGR | Coliform Growth Response |
| CGR | Crack Growth Rate |
| CGR | Crop Growth Rate |
| CGRC | Crop Growth Research Chamber |
| CGRO | Compton Gamma-Ray Observatory |
| CGRP | Calcitonin Gene Related Peptide |
| CGTB | Cellular And Genetic Toxicology Branch |