| Acronym | Meaning |
| PSNO | Pseudonatural Orbital |
| PSNS | Pretreatment Standards For New Sources |
| PSOM | Pseudostate Optical Model |
| PSP | Pressure-sensitive Paint |
| PSP | Pancreatic Stone Protein |
| PSP | Paralytic Shellfish Poison |
| PSP | Progressive Supranuclear Palsy |
| PSPC | Position Sensitive Proportional Counter |
| PSPR | Perfectly Stirred Pulsed Reactor |
| PSRA | Pulse Surface Reaction Rate Analysis |
| PSRG | Position-space Renormalization Group (for D.-of-states Calcns.) |
| PSRI | Planetary Sciences Research Institute |
| PSRP | Process To Significantly Reduce Pathogens (of EPA) |
| PSS | Perturbed Stationary State |
| PSS | Primary Sewage Sludge |
| PSSCF | Pseudo SCF |
| PSSR | Perturbed Stationary State With Relativistic Effects |
| PST | Porcine Somatotropin |
| PSTC | Pressure Sensitive Tape Council |
| PSTL | Photostimulated Thermoluminescence |
| PSTM | Photon Scanning Tunneling Microscopy |
| PSU | Practical Salinity Units |
| PSXD | Position Sensitive X-ray Detector |
| PSZ | Partially-stabilized Zirconia |
| PT | Perturbation Theory |
| PT-MVD | Perturbation Theory (with) Mass-velocity And Darwin (operators) |
| PT2D | Second-order Perturbation Theory (with) Diagonal (part Of Fock Matrix) |
| PT2F | Second-order Perturbation Theory (with) Fock (matrix) |
| PTA | Packed Tower Aeration |
| PTA | Plasma Transferred Arc |
| PTA | Pulse Thermal Analysis |
| PTAW | Plasma Transfer Arc Weld |
| PTB | Phosphotyrosine Binding |
| PTC | Phase Transfer Catalysis |
| PTC | Positive Temperature Coefficient [elec. Conducting Material] |
| PTCA | Percutaneous Transluminal Coronary Angioplasty |
| PTCR | Positive Temperature Coefficient Of Resistance (of Semiconductors) |
| PTD | Probable Toxic Dose |
| PTD | Photothermal Deflection |
| PTD | Protein Transduction Domain |
| PTDS | Photothermal Deflection Spectroscopy |
| PTEAM | Particle Total Exposure Assessment Methodology |
| PTEF | Photochem. Thermodynamic Efficiency Factor |
| PTEN | Phosphatase And Tensin Homolog (mutated In Multiple Advanced Cancers 1) |
| PTGC | Programmed-temperature Gas Chromatography |
| PTGF | Perturbative-type Green Function |
| PTGS | Picosecond Transient Grating Spectroscopy |
| PTGS | Post-transcriptional Gene Silencing |
| PTH | Parathyroid Hormone |
| PTI | Positive Thermal Ionization (for Mass Spectrometry) |