| Acronym | Meaning |
 | OCOKA | Observation |
| OCR | Optical Character Recognition |
| OCS | See Entry |
| OD | Old Dragon - Ordnance Datum (nautical Charts) -Overdose |
| ODAS | OCA-DLR Asteroid Survey |
| ODB | Operational Data Base -Oxford Dictionary Of Byzantium |
| ODBC | Open DataBase Connectivity |
| OEA | (U.S.) Office Of Economic Adjustment |
| OECD | Organization For Economic Co-operation And Development (international) |
| OED | Oxford English Dictionary |
| OEG | Operation Exposure Guidance |
| OEM | Original Equipment Manufacturer |
| OFA | Occipital Face Area |
| OFDA | U.S. AID?s Office Of Foreign Disaster Assistance |
| OGC | Open Geospatial Consortium |
| OGD | Other Government Department |
| OGO | Other Government Organization |
| OGX | OUARGLA -a Petrolium State In The South Of Algeria |
| OH | Ohio (postal Symbol) |
| OHC | OverHead-Cam Engine |
| OHHLA | Original Hip-Hop Lyrics Archive |
| OHIP | Ontario Health Insurance Plan |
| OHP | Observatoire De Haute-Provence |
| OHSS | Ovarian Hyperstimulation Syndrome |
| OIC | Officer In Charge |
| OIE | World Organisation For Animal Health (originally The Office International Des ?pizooties |
| OIF | Operation Iraqi Freedom |
| OIOC | Oriental & India Office Collections (in The British Library) |
| OJ | Orange Juice - O.J. Simpson |
| OJ | Anishinaabe Language (Ojibwa) (ISO 639-1 Code) |
| OJI | Anishinaabe Language (Ojibwa) (ISO 639-2 Code) |
| OJT | On-the-Job Training |
| OK | Oklahoma (postal Symbol) -oll Korrect (facetious Alteration Of All Correct |
| OLED | Organic Light-Emitting Diode |
| OLS | Operational Linescan System |
| OM | Oman (ISO 3166 Digram) |
| OM | Oromo Language (ISO 639-1 Code) |
| OMA | Open Mobile Alliance - Operations & Maintenance |
| OMB | U.S. Office Of Management And Budget - Ontario Municipal Board -Order Of Mapungubwe In Bronze |
| OMD | Orchestral Manoeuvres In The Dark (1980s Pop Group) |
| OME | Osaka Mercantile Exchange |
| OMG | Object Management Group - Oh |
| OMN | Oman (ISO 3166 Trigram) |
| OMP | Order Of Mapungubwe In Platinum |
| OMR | Omani Rial (ISO 4217 Currency Code) |
| OMS | Order Of Mapungubwe In Silver |
| OMT | Object Model Template |
| ON | Ontario (postal Symbol) |
| ONC | Orthopaedic Nurse Certified |
| ONCE | Organizaci›n Nacional De Ciegos Espa?oles (Spanish |
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