| Acronym | Meaning |
 | TM | Terametre - Thulium |
| TM! | Tenchi Muyo! |
| TMA | Terminal Manoeuvring Area (restricted Flying Zone) |
| TMA | Texas Medical Association |
| TMAP | Texas Medication Algorithm Project |
| TMD | Theatre Missile Defence |
| TMI | Too Much Information (Internet Slang) |
| TMJ | TemporoMandibular Joint (syndrome) |
| TMM | Turkmen Manat (ISO 4217 Currency Code) |
| TMNT | Teenage Mutant Ninja Turtles |
| TMP | East Timor (ISO 3166 Trigram; Obsolete 2002) -Temporary |
| TMPG | Transparent Multi-Platform Gateway |
| TMR | Twin Main Rotors (helicopter Type) |
| TMS | Transcranial Magnetic Stimulation |
| TMT | Thirty Meter Telescope |
| TMTOWTDI | There's More Than One Way To Do It (from Perl) |
| TN | Tennessee (postal Symbol) - Teranewton - Tonga (FIPS 10-4 Country Code) - Tunisia (ISO 3166 Digram) |
| TN | Tswana Language (ISO 639-1 Code) |
| TNA | Total Nonstop Action Wrestling |
| TND | Tunisian Dinar (ISO 4217 Currency Code) |
| TNO | Trans-Neptunian Object |
| TNT | TriNitroToluene |
| TO | Togo (FIPS 10-4 Country Code) - Tonga (ISO 3166 Digram) |
| TO | Tongan Language (ISO 639-1 Code) |
| TOA | Table Of Authorities - Total Obligation Authority (accounting) |
| TOAD | Temporary |
| TOC | Table Of Contents - Tactical Operations Centre -Temporo-Occipital Transition Cortex |
| TOGS | Thermal Observation Gunnery Sight |
| TOMS | Total Ozone Mapping Spectrometer (satellite Instrument) |
| TON | Tonga (ISO 3166 Trigram) |
| TON | Tongan Language (ISO 639-2 Code) |
| TOP | Tongan Pa'anga (ISO 4217 Currency Code) |
| TOS | Tape Operating System - Terms Of Service - Tramiel Operating System |
| TOT | Time On Target |
| TOW | Tube-launched |
| TP | Trident Ploughshares |
| TP | East Timor (ISO 3166 Digram; Obsolete 2002) - S?o Tom? And Prncipe (FIPS 10-4 Country Code) -Training Practice |
| TPO | Thrombopoietin |
| TPS | The Pennington School |
| TPTB | The Powers That Be (often Used To Refer To The People Responsible For The Content Of TV Series Or Movies) |
| TR | Turkey (ISO 3166 Digram) |
| TR | Turkish Language (ISO 639-1 Code) |
| TRA | Technology Readiness Assessment |
| TRAC | (U.S. Army) TRADOC Analysis Center |
| TRACON | Terminal Radar Approach Control |
| TRADOC | (U.S. Army) Training And Doctrine Command |
| TRAIN | Tourist Railway Association |
| TRANSCOM | U.S. Transportation Command |
| TRAP | Tactical Receive Equipment And Related Applications |
| TRASANA | TRADOC Systems Analysis Agency |
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