| Acronym | Meaning |
 | LOP | Input/Output Processor |
| LOP | Integrated Operation Plan |
| LOR | Lunar Orbit Rendezvous |
| LORA | Level Of Repair Analysis |
| LORAN | Long Range Navigation |
| LOS | Indian Ocean Ship (STDN) |
| LOS | Input/Output Supervision |
| LOS | InstruCtor Operator Station |
| LOS | Lift-Off Simulator |
| LOS | Line Of Sight |
| LOS | Loss Of Signal |
| LOS | Loss Of Sync |
| LOT | Lift-Off Time |
| LOU | Input/Output Unit |
| LOV | Limit Of Visibility |
| LOV | Loss Of Visibility |
| LOWG | Landing Operations Working Group |
| LOX | Liquid Oxygen (LO2 |
| LP | Launch Pad |
| LP | Liquid Propellant |
| LP | Low Pressure |
| LPD | Landing Point Designator |
| LPD | Launch Procedure Document |
| LPDM | List Of Physical Dimensions |
| LPF | Low Pass Filter |
| LPFT | LOPW Pressure Fuel Turboprop |
| LPFT | Low-pressure Fuel Turbopump |
| LPFTP | Low Pressure Fuel Turbopump |
| LPG | Last Page Generator (Distribution List Used In All OMT'S) |
| LPG | Liquid Propellant Gun |
| LPLWS | Launch Pad Lightning Warning System |
| LPM | Lines Per Minute |
| LPOP | Low Pressure Oxidizer Turbopump |
| LPOT | Low-pressure Oxidizer Turbopump |
| LPOTP | Low Pressure Oxidizer Turbopump |
| LPOX | Low Pressure Oxygen |
| LPR | Line Printer |
| LPS | Launch Processing (Processor) System |
| LPS | Launch Processing System |
| LPS | Liters Per Second |
| LPS/CDS | LPS/Central Data Subsystem |
| LPTTL | Low Power Transistor-Transistor Logic |
| LPW | Lumens Per Watt |
| LR | Landing Radar |
| LR | Launch Right |
| LR | Left Rudder |
| LR | Lower Right |
| LR/LD | Line Receiver/Line Driver |
| LRECL | Logical Records Of Fixed Length |
| LRF | Liquid Rocket Fuel |
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