| Acronym | Meaning |
 | HAM | Height Adjustment Maneuver |
| HAP | Hardware Allocation Panel |
| HAS | Holddown Alignment Support |
| HAS | Hydraulic Actuation System |
| HAS | Hydrogen Actuation System |
| HAST | High Altitude Supersonic Target |
| HAW | Hawaii (STDN) |
| HB | Handbook |
| HB | High Bay |
| HBR | High Bit Rate |
| HBT | Heflex Bio-Engineering Test |
| HBW | Hot Bridge Wire |
| HC | Hand Controller |
| HC | Head Count |
| HC | Hybrid Computer |
| HCED | Hand Controller Engage Driver |
| HCF | High Cycle Fatigue |
| HCF | HIM Configuration File |
| HCL | Horizontal Centerline |
| HCM | Hard Copy Module |
| HCMM | Heat Capacity Mapping Mission |
| HCR | High Cross Range |
| HCSI | Hughes Communications Services |
| HCSL | Hybrid Computation And Simulation Laboratory |
| HCU | Hydraulic Charging Unit |
| HCV | Hydrogen Check Valve |
| HD | Heavy Duty |
| HD | Highly Desirable |
| HD | Hoiddown |
| HD | Horizontal Drain |
| HD | Hydrogen Drain |
| HDA | Housekeeping Data Acquisition |
| HDC | Hasselblad Data Camera |
| HDC | HYbrid Device Controller |
| HDDR | High-Density Digital Recorder |
| HDG | Heading |
| HDP | Holddown Post |
| HDQ | Headquarters |
| HDR | High Data Rate |
| HDR | High Data Rate |
| HDRA | High Data Rate Assembly |
| HDRM | High Data Rate Multiplexer |
| HDRR | High Data Rate Recorder |
| HDRR | High-data-rate Recorder |
| HDRSS | High Data Rate Storage System |
| HDS | Hardware DescriPtion Sheet |
| HDST | Headset |
| HDW | Hardware |
| HDWE | Hardware |
| HE | Heat Exchange (Exchanger) |
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