| Acronym | Meaning |
 | TTU | Timing Terminal Unit |
| TTV | Termination |
| TTY | Teletype |
| TU | Technical Utilization |
| TU | Technology Utilization |
| TU | Transport Unit |
| TUL | Tula Peak |
| TURB | Turbine |
| TV | Television |
| TV | Thermal Vacuum |
| TV | Thrust Vector |
| TV | Transport Vehicle |
| TVA | Thrust Vector Alignment |
| TVAR | Test Variance |
| TVC | Thermal Vacuum Chamber |
| TVC | Thrust Vector Control |
| TVC | Thrust Vector Control |
| TVCA | Thrust Vector Control Actuator |
| TVCD | Thrust Vector Control Driver |
| TVCS | Thrust Vector Control System |
| TVEXPIS | TV Experiment Interconnecting Station |
| TVN | Test Verification Network |
| TVP | Test Verification Program |
| TVS | Toxic Vapor Suit |
| TVSA | Thrust Vector Control Servoamplifier |
| TVSSIS | TV Subsystem Interconnecting Station |
| TVT | Thermal Vacuum Test |
| TVTA | Thermal Vacuum Test Article |
| TW | Tailwind |
| TW | Thumbwheel |
| TW | Time Words |
| TW | Traveling Wave |
| TWD | Twisted Double Shielded |
| TWL | Total Weight Loss |
| TWR | Tower |
| TWT | Traveling Wave Tube |
| TWT | Trisonic Wind Tunnel (Rockwell) |
| TWTA | Traveling Wave Tube Amplifier |
| TWX | Teletype Wire Transmission |
| TX | Translation Hand Controller X-Axis Direction |
| TX | Transmit Channel |
| TX/RX | Transmitter/Receiver |
| TY | Translation Hand Controller Y-Axis Direction |
| TYP | Typical |
| TZ | Translation Hand Controller Z-Axis Direction |
| U | Underfloor |
| U | Uranium |
| U-SB | Unified S-Band |
| U/C | Under Current |
| U/D | Update |
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