| Acronym | Meaning |
 | TICM | Test Interface And Control Module |
| TIFS | Total In-Flight Simulator |
| TIG | Time Of Ignition |
| TIM | Technical Interchange Meeting |
| TIM | Time Interval Monitor |
| TIMED | Thermosphere, Ionosphere, Mesosphere, Energy, And Dynamics Mission |
| TIO | Target Insertion Orbit |
| TIP | Thrust Inlet Pressure |
| TIROS | ToPographical Infrared Operations Satellite |
| TIS | Test Interface Subsystem |
| TK | Tank |
| TL | Lot Traceability |
| TL | Thrust Level |
| TL | Time Latest |
| TL | Transient Load |
| TLC | Telecommand |
| TLCE | Transmission Line Conditioning Equipment |
| TLL | Tooling Inspection Instrumentation |
| TLM | Telemetry |
| TLM | Telemetry |
| TLS | Time Line Sheet |
| TLS | Top Left Side |
| TLSA | Torso Limb Suit Assembly |
| TLV | Threshold Limit Value |
| TLV | Transporter-Loader Vehicle |
| TM | Member Traceability |
| TM | Table Maintenance |
| TM | Technical Management |
| TM | Telemetry |
| TM | Time Management |
| TM | TrafficModel |
| TMB | Transportation Management Bulletin |
| TMBU | Table Maintenance Block Update |
| TMC | Test Monitoring Console |
| TMECO | Time Of Main Engine Cutoff |
| TMF | Transporter Maintenance Facility |
| TMG | Thermal Meteoroid Garment |
| TMI | Technical Management Items |
| TMO | Test Manufacturing Order |
| TMO | Tool Manufacturing Order |
| TMP | Terminal Panel |
| TMP | Time Management Processor |
| TMPRY | Temporary |
| TMPV | Torquemotor Pilot Valve |
| TMR | Timer |
| TMU | Temperature Measurement Unit |
| TN | Technical Note |
| TNL | Tunnel |
| TNT | Trinitrotoluene |
| TO | Operations Management (KSC Directorate) |
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