| Acronym | Meaning |
 | REM | Release Engine Mechanism |
| REM | Release Engine Module |
| REM | Release Escape Mechanism |
| REM | Release-Engage Mechanism |
| REM | Roentgen Equivalent In Man |
| REN | RAD Rendezvous Radar |
| REND | Rendezvous |
| REO | Request |
| REO | Require |
| REOD | Required |
| REPL | Replace |
| REPR | Repressurization |
| REPRO | Reproduction |
| REQN4TS | Requirements (RQN4TS Preferred) |
| RES | Reserve |
| RES | Reservoir |
| RESID | Residual |
| RESIS | Resistance |
| RESP | Responsibility |
| RESVR | Reservoir |
| RET | Retract |
| RETEN | Retention |
| RETRO | Retro Controller (NASA) |
| RETRO | Retrofire |
| RETRO | Retrofire Officer |
| RETRV | Retrieve |
| REV | Reverse |
| REV | Review |
| REV | Revision |
| REV | Revolution |
| RF | Communications Support |
| RF | Radio Frequency |
| RF | Radio Frequency |
| RF | Right Forward |
| RF-TK | Radio Frequency Tracking |
| RFA | Request For Action |
| RFA | RF Authorization (Frequency) |
| RFB | Ready For Baseline |
| RFB | Request For Bid |
| RFC | Radio Frequency Charts |
| RFC | Request For Change |
| RFC | Request For Change Revolution |
| RFCP | Request For Computer Program |
| RFD | Requirements Formulation Document |
| RFE | Request For Estimate |
| RFEI | Request For Engineering Information |
| RFI | Radio Frequency Interference |
| RFI | Remote Facility Inquiry |
| RFI | Remote File Inquiry |
| RFI | Request For Information |
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