| Acronym | Meaning |
 | PMU | Pulse Modulation Unit |
| PN | Part Number (P/N Preferred) |
| PN | Pseudo Noise |
| PN | Pseudo-Random Noise |
| PNEU | Pneumatic |
| PNL | Panel |
| PNP | Prenegotiation Position |
| PO | Personnel Office (KSC Directorate) |
| PO | Postorbit |
| PO | PurchaseOrder |
| POA | Plan Of Action |
| POC | PaYload Operations Center |
| POC | Purchase Order Closeout |
| POCC | Payload Operations Control Center |
| POCC | Payload Operations Control Center |
| POCN | Purchase Order Change Notice |
| POD | Payload Operations Division (JSC) |
| POE | Proximity OPticai Device |
| POGO | P090 Suppression System |
| POGO | Pilot Operational EquiPment |
| POGO | Polar Orbiting GeophYsical Observatory |
| POI | Product Of Inertia |
| POI | Propellant Quantity Indicator |
| POL | Petroleum, Oil, And Lubricant |
| POLAR | Production Order Location And Reporting |
| POM | Pallet-Only Mode |
| POM | Printer OutPut Microfilm |
| POMT | Planning Operations Management Team |
| POP | Perpendicular-to-Orbit Plane |
| POP | Preburner Oxidizer Pump |
| POP | Preflight Operations Procedures |
| POP | Prelaunch Operations Plan |
| POP | Program Operating Plan |
| POPA | PaYload Ordnance Processing Area |
| POPU | Push Over Pull Up |
| POR | Point Of Resolution |
| POR | Purchase Order Request |
| PORB | Production Operations Review Board |
| PORCN | Production Oi-der Records Change Notice |
| PORD | Performance And 0iperations Requirements Document |
| PORR | Preliminary Operat Ons Requirements Review |
| PORT | Portable |
| POS | Pacific Ocean Ship |
| POS | Portable Oxygen System |
| POS | Portable Oxygen System |
| POS | Position |
| POST | Payload Operations SuPport Team |
| POST | Positive |
| POST | Program To OPtimize Simulated Trajectories |
| POT | Potable |
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